X
Approved indication:
  • No approved nephrology disease indications – used for immunosuppressive qualities

MOA:
  • Inhibition of T cells to prevent lymphokine production and release20

Dosing:
  • 3-5mg/kg daily10

Adverse effects:
  • Renal dysfunction, tremor, hirsutism, hypertension, gum hyperplasia20

Black box warning (summary):
  • Increased risk of infection and neoplasm
  • Potential renal dysfunction, including structural kidney damage20
Treatment for:

Approved indication:
  • No approved nephrology disease indications – used for immunosuppressive qualities

MOA:
  • Inhibits T cell activation, though exact mechanism is unknown21

Dosing:
  • 0.05-0.1mg/kg daily10

Adverse effects:
  • Infections, hypertension, tremor, abnormal renal function21
Black box warning (summary):
  • Increased risk of serious infections and malignancies21
Treatment for: