Approved indication:

• No approved nephrology disease indications – used for immunosuppressive qualities

MOA:

• Depletes guanosine nucleotides in T and B lymphocytes and inhibits their proliferation, thereby creating immunosuppression²²

Dosing:

• 500-1000 mg twice daily¹⁰

Adverse effects:

• Diarrhea, infections, sepsis, leukopenia, vomiting²²

Treatment for: